Identification of Mechanism and Pathway of the Interaction between the African Traditional Medicine, Sutherlandia Frutescens, and the Antiretroviral Protease Inhibitor, Atazanavir, in Human Subjects Using Population Pharmacokinetic (PK) Analysis

• Main Authors: Adrienne Carmel Muller (Author), Murray P Ducharme (Author), Isadore Kanfer (Author)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2018-08-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Although the use of the indigenous Southern African plant, Sutherlandia frutescens (SF) for the treatment of HIV/AIDS has previously been described, the risk which it may pose to the safety and efficacy of ARVs and the potential mechanisms which underlie such effects may have clinical significance a...