The Challenges of Recombinant Endostatin in Clinical Application: Focus on the Different Expression Systems and Molecular Bioengineering

• Main Authors: Abbas Mohajeri (Author), Sarvin Sanaei (Author), Farhad Kiafar (Author), Amir Fattahi (Author), Majid Khalili (Author), Nosratollah Zarghami (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2017-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Angiogenesis plays an essential role in rapid growing and metastasis of the tumors. Inhibition of angiogenesis is a putative strategy for cancer therapy. Endostatin (Es) is an attractive anti-angiogenesis protein with some clinical application challenges including; short half-life, instability in se...