Metformin Attenuates Neutrophil Recruitment through the H3K18 Lactylation/Reactive Oxygen Species Pathway in Zebrafish

• Main Authors: Ren Zhou (Author), Rui-Chen Ding (Author), Qian Yu (Author), Cheng-Zeng Qiu (Author), Hao-Yi Zhang (Author), Zong-Jun Yin (Author), Da-Long Ren (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Beyond its well-established role in diabetes management, metformin has gained attention as a promising therapeutic for inflammation-related diseases, largely due to its antioxidant capabilities. However, the mechanistic underpinnings of this effect remain elusive. Using in vivo zebrafish models of i...