Chitosan-Coated Nanoparticles: Effect of Chitosan Molecular Weight on Nasal Transmucosal Delivery

• Main Authors: Franciele Aline Bruinsmann (Author), Stefania Pigana (Author), Tanira Aguirre (Author), Gabriele Dadalt Souto (Author), Gabriela Garrastazu Pereira (Author), Annalisa Bianchera (Author), Laura Tiozzo Fasiolo (Author), Gaia Colombo (Author), Magno Marques (Author), Adriana Raffin Pohlmann (Author), Silvia Stanisçuaski Guterres (Author), Fabio Sonvico (Author)
• Format: Book
• Published: MDPI AG, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drug delivery to the brain represents a challenge, especially in the therapy of central nervous system malignancies. Simvastatin (SVT), as with other statins, has shown potential anticancer properties that are difficult to exploit in the central nervous system (CNS). In the present work the physico⁻...