Chitosan-Coated Nanoparticles: Effect of Chitosan Molecular Weight on Nasal Transmucosal Delivery

• Главные авторы: Franciele Aline Bruinsmann (Автор), Stefania Pigana (Автор), Tanira Aguirre (Автор), Gabriele Dadalt Souto (Автор), Gabriela Garrastazu Pereira (Автор), Annalisa Bianchera (Автор), Laura Tiozzo Fasiolo (Автор), Gaia Colombo (Автор), Magno Marques (Автор), Adriana Raffin Pohlmann (Автор), Silvia Stanisçuaski Guterres (Автор), Fabio Sonvico (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2019-02-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Drug delivery to the brain represents a challenge, especially in the therapy of central nervous system malignancies. Simvastatin (SVT), as with other statins, has shown potential anticancer properties that are difficult to exploit in the central nervous system (CNS). In the present work the physico⁻...