Polymorphisms of Catechol-O-Methyl Transferase (COMT) Gene in Vulnerability to Levodopa-Induced Dyskinesia

• 主要な著者: Svetlana A. Ivanova (著者), Valentina M. Alifirova (著者), Ivan V. Pozhidaev (著者), Maxim B. Freidin (著者), Irina A. Zhukova (著者), Diana Z. Osmanova (著者), Natalia G. Zhukova (著者), Yulia A. Mironova (著者), Vladimir V. Tiguntsev (著者), Olga Yu. Fedorenko (著者), Nikolay A. Bokhan (著者), Bob Wilffert (著者), Anton J.M. Loonen (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2018-08-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Purpose. Parkinson's disease (PD), a common neurodegenerative disorder, is usually treated with Levodopa (L-DOPA). The use of this drug, however, is severely limited by the development of side effects of the motor system: Levodopa-induced dyskinesia (LID). The aim of this study is to investigat...