HABIT efficacy and sustainability trial, a multi-center randomized controlled trial to improve hydroxyurea adherence in youth with sickle cell disease: a study protocol

• Main Authors: Arlene Smaldone (Author), Deepa Manwani (Author), Banu Aygun (Author), Kim Smith-Whitley (Author), Haomiao Jia (Author), Jean-Marie Bruzzese (Author), Sally Findley (Author), Joshua Massei (Author), Nancy S. Green (Author)
• Format: Book
• Published: BMC, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Hydroxyurea (HU) is recommended as standard practice for youth with sickle cell disease (SCD). Yet, despite its efficacy, HU adherence in adolescents and young adults is often poor. Poor medication adherence increases disease burden, healthcare cost and widens health disparities....