Gas6/Axl Axis Activation Dampens the Inflammatory Response in Osteoarthritic Fibroblast-like Synoviocytes and Synovial Explants

• मुख्य लेखकों: Juliana P. Vago (लेखक), Natália Valdrighi (लेखक), Esmeralda N. Blaney-Davidson (लेखक), Daniel L. A. H. Hornikx (लेखक), Margot Neefjes (लेखक), María E. Barba-Sarasua (लेखक), Nathalie G. M. Thielen (लेखक), Martijn H. J. van den Bosch (लेखक), Peter M. van der Kraan (लेखक), Marije I. Koenders (लेखक), Flávio A. Amaral (लेखक), Fons A. J. van de Loo (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Osteoarthritis (OA) is the most prevalent joint disease, and it is characterized by cartilage degeneration, synovitis, and bone sclerosis, resulting in swelling, stiffness, and joint pain. TAM receptors (Tyro3, Axl, and Mer) play an important role in regulating immune responses, clearing apoptotic c...