Vitamin C influences antioxidative, anti-inflammatory and wound healing markers in smokers' gingival fibroblasts in vitro

• Main Authors: Ruaa Alyami (Author), Reham Al Jasser (Author), Fahad Ali Alshehri (Author), Nouf Alshibani (Author), Sarah Bin Hamdan (Author), Riham Abdulaziz Alyami (Author), Abdurahman A. Niazy (Author)
• Format: Book
• Published: Elsevier, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Saudi Arabia has an overall smoking rate of 15.9%. The link between smoking and periodontal disease has been studied extensively. It is possible for human gingival fibroblasts to accumulate nicotine intracellularly over a period of four hours. Additionally, unmetabolized nicotine is rele...