Optimization and in-vivo evaluation of isradipine nanoparticles using Box-Behnken design surface response methodology

The isradipine is the potent anti hypertensive drug, which is matrix in polymeric nanoparticle by using solvent evaporation method. In this work, 3-factor, 3-level Box-Behnken design was used to optimize the process parameters like polymer concentration (A), sonication frequency (B) and sonication t...

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Main Authors: Vijayan Venugopal (Author), K. Jayaraja Kumar (Author), S. Muralidharan (Author), S. Parasuraman (Author), P. Vasanth Raj (Author), K. Venkates Kumar (Author)
Format: Book
Published: Elsevier, 2016-01-01T00:00:00Z.
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