Effect of tissue permeability and drug diffusion anisotropy on convection-enhanced delivery

• Asıl Yazarlar: Wenbo Zhan (Yazar), Ferdinando Rodriguez y Baena (Yazar), Daniele Dini (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Although convection-enhanced delivery (CED) can successfully facilitate a bypass of the blood brain barrier, its treatment efficacy remains highly limited in clinic. This can be partially attributed to the brain anisotropic characteristics that lead to the difficulties in controlling the drug spatia...