Injectable SN-38-embedded Polymeric Microparticles Promote Antitumor Efficacy against Malignant Glioma in an Animal Model

• Main Authors: Yuan-Yun Tseng (Author), Tao-Chieh Yang (Author), Shu-Mei Chen (Author), Shun-Tai Yang (Author), Ya-Ling Tang (Author), Shih-Jung Liu (Author)
• Format: Book
• Published: MDPI AG, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Malignant glioma (MG) is extremely aggressive and highly resistant to chemotherapeutic agents. Using electrospraying, the potent chemotherapeutic agent 7-ethyl-10-hydroxycamptothecia (SN-38) was embedded into 50:50 biodegradable poly[(<span style="font-variant: small-caps;">d,l</s...