Specific protease mutation patterns are associated with oropharyngeal candidiasis in a New Orleans patient cohort of HIV-infected individuals

• Main Authors: Peter J. Hickman (Author), Robertino M. Mera (Author), Janet E. Leigh (Author), Paul L. Fidel Jr (Author), Allen R. Mock (Author), William R. Gallaher (Author), Ronald B. Luftig (Author)
• Format: Book
• Published: Universidade Estadual de Campinas, 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

HIV-1 protease gene sequences were obtained from peripheral blood, saliva or oral tissues of 35 HIV+ patients using nested amplification and manual sequencing of PCR products. Of the 35 HIV+ patients 9 had clinical oropharyngeal candidiasis (OPC) while 26 did not, and only 4 patients were on proteas...