Assessment of solid microneedle rollers to enhance transmembrane delivery of doxycycline and inhibition of MMP activity

• Main Authors: Abbie Omolu (Author), Maryse Bailly (Author), Richard M. Day (Author)
• פורמט: ספר
• יצא לאור: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Many chronic wounds exhibit high matrix metalloproteinase (MMP) activity that impedes the normal wound healing process. Intradermal delivery (IDD) of sub-antimicrobial concentrations of doxycycline, as an MMP inhibitor, could target early stages of chronic wound development and inhibit further wound...