Development and Validation of an Up-to-Date Highly Sensitive UHPLC-MS/MS Method for the Simultaneous Quantification of Current Anti-HIV Nucleoside Analogues in Human Plasma

• Main Authors: Amedeo De Nicolò (Author), Alessandra Manca (Author), Alice Ianniello (Author), Alice Palermiti (Author), Andrea Calcagno (Author), Micol Ferrara (Author), Miriam Antonucci (Author), Jessica Cusato (Author), Valeria Avataneo (Author), Elisa De Vivo (Author), Stefano Bonora (Author), Francesco Giuseppe De Rosa (Author), Giovanni Di Perri (Author), Antonio D'Avolio (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Therapeutic options to treat HIV infection have widened in the past years, improving both effectiveness and tolerability, but nucleoside reverse transcriptase inhibitors (NRTIs) are still considered the standard backbone of the combination regimens. Therapeutic drug monitoring (TDM) can be useful fo...