Natural resistance to ascorbic acid induced oxidative stress is mainly mediated by catalase activity in human cancer cells and catalase-silencing sensitizes to oxidative stress

• Asıl Yazarlar: Klingelhoeffer Christoph (Yazar), Kämmerer Ulrike (Yazar), Koospal Monika (Yazar), Mühling Bettina (Yazar), Schneider Manuela (Yazar), Kapp Michaela (Yazar), Kübler Alexander (Yazar), Germer Christoph-Thomas (Yazar), Otto Christoph (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2012-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Ascorbic acid demonstrates a cytotoxic effect by generating hydrogen peroxide, a reactive oxygen species (ROS) involved in oxidative cell stress. A panel of eleven human cancer cell lines, glioblastoma and carcinoma, were exposed to...