Nanotherapy for bone repair: milk-derived small extracellular vesicles delivery of icariin

• Main Authors: Xinxin Yu (Author), Ming Dong (Author), Lina Wang (Author), Qian Yang (Author), Long Wang (Author), Wenqing Han (Author), Juhong Dong (Author), Tingjiao Liu (Author), Ying Kong (Author), Weidong Niu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractIcariin (ICA) played an important role in the treatment of inflammatory bone defects. However, pharmacokinetic studies have shown that its poor bioavailability limited its application. In this context, we isolated bovine milk-derived sEV and prepared sEV-ICA to improve the osteogenic effect...