Intravenous and oral whole body ketone dosimetry, biodistribution, metabolite correction and kinetics studied by (R)-[1-11C]β-hydroxybutyrate ([11C]OHB) PET in healthy humans

• المؤلفون الرئيسيون: Thien Vinh Luong (مؤلف), Erik Nguyen Nielsen (مؤلف), Lise Falborg (مؤلف), Mette Louise Gram Kjærulff (مؤلف), Lars Poulsen Tolbod (مؤلف), Esben Søndergaard (مؤلف), Niels Møller (مؤلف), Ole Lajord Munk (مؤلف), Lars Christian Gormsen (مؤلف)
• التنسيق: كتاب
• منشور في: SpringerOpen, 2023-06-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract Background Ketones are increasingly recognized as an important and possibly oxygen sparing source of energy in vital organs such as the heart, the brain and the kidneys. Drug treatments, dietary regimens and oral ketone drinks designed to deliver ketones for organ and tissue energy producti...