Cytomegalovirus acquisition in infancy and the risk of tuberculosis disease in childhood: a longitudinal birth cohort study in Cape Town, South Africa

• Main Authors: Leonardo Martinez, PhD (Author), Mark P Nicol, ProfPhD (Author), Catherine J Wedderburn, MRCPCH (Author), Attie Stadler, MPH (Author), Maresa Botha, MBChB (Author), Lesley Workman, MPH (Author), David M le Roux, MBChB (Author), Heather J Zar, ProfPhD (Author)
• Formato: Libro
• Publicado: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Summary: Background: The risk of tuberculosis disease after recent exposure is greatest before age 5 years; however, the mechanisms explaining this increased risk are not well elucidated. Acquisition of viral infections, such as cytomegalovirus, in early life might modulate the immune system. We aim...