Quantitative Analysis of the Phase Transition Mechanism Underpinning the Systemic Self-Assembly of a Mechanopharmaceutical Device

Quantitative Analysis of the Phase Transition Mechanism Underpinning the Systemic Self-Assembly of a Mechanopharmaceutical Device

Clofazimine (CFZ) is a poorly soluble, weakly basic, small molecule antibiotic clinically used to treat leprosy and is now in clinical trials as a treatment for multidrug resistant tuberculosis and COVID-19. CFZ exhibits complex, context-dependent pharmacokinetics that are characterized by an increa...

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Main Authors: Steven Dunne (Author), Andrew R. Willmer (Author), Rosemary Swanson (Author), Deepak Almeida (Author), Nicole C. Ammerman (Author), Kathleen A. Stringer (Author), Edmund V. Capparelli (Author), Gus R. Rosania (Author)
Format: Book
Published: MDPI AG, 2021-12-01T00:00:00Z.
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