Paternal Programming of Liver Function and Lipid Profile Induced by a Paternal Pre-Conceptional Unhealthy Diet: Potential Association with Altered Gut Microbiome Composition

• Main Authors: Xiaoli Zhang (Author), Yunpeng Dong (Author), Guoying Sun (Author), Ahmed A. Hasan (Author), Mei Tian (Author), Suimin Zeng (Author), Jing Li (Author), Shiyu Zeng (Author), Jun Ma (Author), Jian Li (Author), Berthold Hocher (Author)
• Format: Book
• Published: Karger Publishers, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Paternal exposure to adverse environmental conditions can act on offspring's phenotype and influence offspring's later life disease risk. Our study was designed to examine the effect of feeding male rats before mating a high-fat, high-sucrose and high-salt diet (HFSSD) ove...