Core Structure-Activity Relationship Studies of 5,7,20-<i>O</i>-Trimethylsilybins in Prostate Cancer Cell Models

• Main Authors: Sitong Wu (Author), Guanglin Chen (Author), Eva Y. Chen (Author), Leyla S. Farshidpour (Author), Qiang Zhang (Author), Guangdi Wang (Author), Qiao-Hong Chen (Author)
• Format: Book
• Published: MDPI AG, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Silibinin, also known as silybin, is isolated from milk thistle (<i>Silybum marianum</i>). Silibinin has been demonstrated to be a good lead compound due to its potential to prevent and treat prostate cancer. Its moderate potency and poor pharmacokinetic profile hindered it from moving f...