EFNA4 promotes cell proliferation and tumor metastasis in hepatocellular carcinoma through a PIK3R2/GSK3β/β-catenin positive feedback loop

• Main Authors: Junhao Lin (Author), Chunting Zeng (Author), JiaKang Zhang (Author), Zhenghui Song (Author), Na Qi (Author), Xinhui Liu (Author), Ziyan Zhang (Author), Aimin Li (Author), Fengsheng Chen (Author)
• Format: Book
• Published: Elsevier, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rapid tumor progression, metastasis, and diagnosis in advanced stages of disease are the main reasons for the short survival time and high mortality rate of patients with hepatocellular carcinoma (HCC). Ephrin A4 (EFNA4), the ligand of the EPH family, participates in the development of blood vessels...