A novel step‐down infusion method of barbiturate therapy: Its safety and effectiveness for intracranial pressure control

• Main Authors: Yukako Yamakawa (Author), Motohiro Morioka (Author), Tetsuya Negoto (Author), Kimihiko Orito (Author), Munetake Yoshitomi (Author), Yukihiko Nakamura (Author), Nobuyuki Takeshige (Author), Masafumi Yamamoto (Author), Yasuharu Takeuchi (Author), Kazutaka Oda (Author), Hirofumi Jono (Author), Hideyuki Saito (Author)
• Format: Book
• Published: Wiley, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Intracranial pressure (ICP) has to be maintained quite constant, because increased ICP caused by cerebrovascular disease and head trauma is fatal. Although controlling ICP is clinically critical, only few therapeutic methods are currently available. Barbiturates, a group of sedative‐hypnoti...