Aidi injection reduces doxorubicin-induced cardiotoxicity by inhibiting carbonyl reductase 1 expression

• Main Authors: Yuan Lu (Author), Wen Liu (Author), Ting Lv (Author), Yanli Wang (Author), Ting Liu (Author), Yi Chen (Author), Yang Jin (Author), Jin Huang (Author), Lin Zheng (Author), Yong Huang (Author), Yan He (Author), Yongjun Li (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Aidi injection (ADI), a traditional Chinese medicine antitumor injection, is usually combined with doxorubicin (DOX) for the treatment of malignant tumours. The cardiotoxicity of DOX is ameliorated by ADI in the clinic. However, the relevant mechanism is unknown.Objective To investigate the...