Mitochondrial Defunctionalization Supresses Tim-3-Galectin-9 Secretory Pathway in Human Colorectal Cancer Cells and Thus Can Possibly Affect Tumor Immune Escape

The Tim-3-galectin-9 secretory pathway is known to protect various types of cancer cells against host immune surveillance. We found that pharmacologically induced mitochondrial dysfunction leads to a reduced galectin-9 expression/exocytosis in human colorectal cancer cells and re-distribution of thi...

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Main Authors: Svetlana S. Sakhnevych (Author), Inna M. Yasinska (Author), Elizaveta Fasler-Kan (Author), Vadim V. Sumbayev (Author)
Format: Book
Published: Frontiers Media S.A., 2019-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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