A closer look at the synthesis of 2-[18F]fluoroethyl tosylate to minimize the formation of volatile side-products

• Hauptverfasser: Martha Sahylí Ortega Pijeira (Verfasst von), Sofia Nascimento dos Santos (Verfasst von), Yasniel Babi Araujo (Verfasst von), André Luis Lapolli (Verfasst von), Marcio Nardelli Wandermuren (Verfasst von), Zalua Rodríguez Riera (Verfasst von), Ivone Carvalho (Verfasst von), Philip H. Elsinga (Verfasst von), Emerson Soares Bernardes (Verfasst von)
• Format: Buch
• Veröffentlicht: SpringerOpen, 2022-10-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Background 2-[18F]Fluoroethyltosylate ([18F]FEtOTs) is a well-known 18F-fluoroalkylating agent widely used to synthesize radiotracers for positron emission tomography. The widespread use of [18F]FEtOTs is due in part to its low volatility when compared to other halide and sulfonate building...