Neferine alleviates chronic stress-induced depression by regulating monoamine neurotransmitter secretion and gut microbiota structure

• Main Authors: Zaiquan Dong (Author), Qinglian Xie (Author), Feiyu Xu (Author), Xiaoling Shen (Author), Yanni Hao (Author), Jin Li (Author), Haizhen Xu (Author), Qiang Peng (Author), Weihong Kuang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neferine (Nef) might possess anti-depressive properties; however, its therapeutic effects are yet to be elucidated. Therefore, in this study, we aimed to explore the anti-depressant property of Nef using a mouse model of chronic stress-induced depression. Fifteen depression-prone mice were randomly...