The Inhibition of Zinc Excitotoxicity and AMPK Phosphorylation by a Novel Zinc Chelator, 2G11, Ameliorates Neuronal Death Induced by Global Cerebral Ischemia

• Hoofdauteurs: Dae Ki Hong (Auteur), Jae-Won Eom (Auteur), A Ra Kho (Auteur), Song Hee Lee (Auteur), Beom Seok Kang (Auteur), Si Hyun Lee (Auteur), Jae-Young Koh (Auteur), Yang-Hee Kim (Auteur), Bo Young Choi (Auteur), Sang Won Suh (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2022-11-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

AMP-activated protein kinase (AMPK) is necessary for maintaining a positive energy balance and essential cellular processes such as glycolysis, gene transcription, glucose uptake, and several other biological functions. However, brain injury-induced energy and metabolic stressors, such as cerebral i...