The Inhibition of Zinc Excitotoxicity and AMPK Phosphorylation by a Novel Zinc Chelator, 2G11, Ameliorates Neuronal Death Induced by Global Cerebral Ischemia

• Glavni autori: Dae Ki Hong (Autor), Jae-Won Eom (Autor), A Ra Kho (Autor), Song Hee Lee (Autor), Beom Seok Kang (Autor), Si Hyun Lee (Autor), Jae-Young Koh (Autor), Yang-Hee Kim (Autor), Bo Young Choi (Autor), Sang Won Suh (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2022-11-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

AMP-activated protein kinase (AMPK) is necessary for maintaining a positive energy balance and essential cellular processes such as glycolysis, gene transcription, glucose uptake, and several other biological functions. However, brain injury-induced energy and metabolic stressors, such as cerebral i...