The Inhibition of Zinc Excitotoxicity and AMPK Phosphorylation by a Novel Zinc Chelator, 2G11, Ameliorates Neuronal Death Induced by Global Cerebral Ischemia

• Main Authors: Dae Ki Hong (Author), Jae-Won Eom (Author), A Ra Kho (Author), Song Hee Lee (Author), Beom Seok Kang (Author), Si Hyun Lee (Author), Jae-Young Koh (Author), Yang-Hee Kim (Author), Bo Young Choi (Author), Sang Won Suh (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AMP-activated protein kinase (AMPK) is necessary for maintaining a positive energy balance and essential cellular processes such as glycolysis, gene transcription, glucose uptake, and several other biological functions. However, brain injury-induced energy and metabolic stressors, such as cerebral i...