Heparin-induced thrombocytopenia: a rare presentation with skin necrosis

• Asıl Yazarlar: Filipa David (Yazar), Ana Catarina Trigo (Yazar), José Ribeiro (Yazar), Joana Cancela (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: PAGEPress Publications, 2023-10-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Heparin-induced thrombocytopenia is the most clinically relevant non-haemorrhagic complication of heparin and is characterised by the presence of anti-PF4/heparin-IgG antibodies. The circulating PF4/heparin-IgG immune complex binds to platelets via their FcyIIa receptors, activating them and promoti...