The Influence of CYP3A4 Genetic Polymorphism and Proton Pump Inhibitors on Osimertinib Metabolism
The aim of this study was to 1) investigate the effects of 27 CYP3A4 variants on the metabolism of osimertinib and 2) study the interactions between osimertinib and others as well as the underlying mechanism. A recombinant human CYP3A4 enzymatic incubation system was developed and employed to determ...
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| Автори: | , , , , , , |
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| Формат: | Книга |
| Опубліковано: |
Frontiers Media S.A.,
2022-03-01T00:00:00Z.
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| Онлайн доступ: | Connect to this object online. |
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Connect to this object online.3rd Floor Main Library
| Шифр: |
A1234.567 |
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| Примірник 1 | Доступно |