Mitochondrial uncoupling attenuates sarcopenic obesity by enhancing skeletal muscle mitophagy and quality control

• 主要な著者: Wagner S. Dantas (著者), Elizabeth R.M. Zunica (著者), Elizabeth C. Heintz (著者), Bolormaa Vandanmagsar (著者), Z. Elizabeth Floyd (著者), Yongmei Yu (著者), Hisashi Fujioka (著者), Charles L. Hoppel (著者), Kathryn P. Belmont (著者), Christopher L. Axelrod (著者), John P. Kirwan (著者)
• フォーマット: 図書
• 出版事項: Wiley, 2022-06-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Background Sarcopenic obesity is a highly prevalent disease with poor survival and ineffective medical interventions. Mitochondrial dysfunction is purported to be central in the pathogenesis of sarcopenic obesity by impairing both organelle biogenesis and quality control. We have previously...