RNA G-Quadruplex within the 5'-UTR of FEN1 Regulates mRNA Stability under Oxidative Stress

• Main Authors: Ying Ma (Author), Yang Yang (Author), Jingyu Xin (Author), Lingfeng He (Author), Zhigang Hu (Author), Tao Gao (Author), Feiyan Pan (Author), Zhigang Guo (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Reactive oxygen species (ROS) are a group of highly oxidative molecules that induce DNA damage, affecting DNA damage response (DDR) and gene expression. It is now recognized that DNA base excision repair (BER) is one of the important pathways responsible for sensing oxidative stress to eliminate DNA...