Novel ophthalmic formulation of myriocin: implications in retinitis pigmentosa

• Main Authors: Chiara Bianca Maria Platania (Author), Michele Dei Cas (Author), Simona Cianciolo (Author), Annamaria Fidilio (Author), Francesca Lazzara (Author), Rita Paroni (Author), Rosario Pignatello (Author), Enrica Strettoi (Author), Riccardo Ghidoni (Author), Filippo Drago (Author), Claudio Bucolo (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Myriocin is an antibiotic derived from Mycelia sterilia, and is a potent inhibitor of serine palmitoyltransferase, the enzyme involved in the first step of sphingosine synthesis. Myriocin, inhibiting ceramide synthesis, has a great potential for treatment of diseases characterized by high ceramide l...