Pleiotropic Effects of Atorvastatin Result in a Downregulation of the Carboxypeptidase U System (CPU, TAFIa, CPB2) in a Mouse Model of Advanced Atherosclerosis
Statins (hydroxymethyl-glutaryl-CoA-reductase inhibitors) lower procarboxypeptidase U (proCPU, TAFI, proCPB2). However, it is challenging to prove whether this is a lipid or non-lipid-related pleiotropic effect, since statin treatment decreases cholesterol levels in humans. In apolipoprotein E-defic...
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Main Authors: | Karen Claesen (Author), Lynn Roth (Author), Joachim C. Mertens (Author), Karlijn Hermans (Author), Yani Sim (Author), Dirk Hendriks (Author) |
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Format: | Book |
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MDPI AG,
2021-10-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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