Antidepressants and Circadian Rhythm: Exploring Their Bidirectional Interaction for the Treatment of Depression

• Hoofdauteurs: Soraia Silva (Auteur), Joana Bicker (Auteur), Amílcar Falcão (Auteur), Ana Fortuna (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2021-11-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Scientific evidence that circadian rhythms affect pharmacokinetics and pharmacodynamics has highlighted the importance of drug dosing-time. Circadian oscillations alter drug absorption, distribution, metabolism, and excretion (ADME) as well as intracellular signaling systems, target molecules (e.g.,...