The Protective Effect of DiDang Tang Against AlCl3-Induced Oxidative Stress and Apoptosis in PC12 Cells Through the Activation of SIRT1-Mediated Akt/Nrf2/HO-1 Pathway

• Main Authors: Jing Lu (Author), Qingxia Huang (Author), Dongmei Zhang (Author), Tianye Lan (Author), Ying Zhang (Author), Xiaolei Tang (Author), Peng Xu (Author), Dexi Zhao (Author), Deyu Cong (Author), Daqing Zhao (Author), Liwei Sun (Author), Xiangyan Li (Author), Jian Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aluminum (Al) is considered a pathological factor for various neurological and neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease (PD). The neurotoxicity of aluminum can cause oxidative brain damage, trigger apoptosis, and ultimately cause irreversible dam...