Causal association of epigenetic aging and osteoporosis: a bidirectional Mendelian randomization study

• Main Authors: Xinyu Liang (Author), Wei Shi (Author), Xinglong Zhang (Author), Ran Pang (Author), Kai Zhang (Author), Qian Xu (Author), Chunlei Xu (Author), Xin Wan (Author), Wenhao Cui (Author), Dong Li (Author), Zhaohui Jiang (Author), Zhengxuan Liu (Author), Hui Li (Author), Huafeng Zhang (Author), Zhijun Li (Author)
• Format: Book
• Published: BMC, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The relationship between aging and osteoporosis is well established. However, the relationship between the body's physiological age, i.e. epigenetic age, and osteoporosis is not known. Our goal is to analyze the bidirectional causal relationship between epigenetic clocks and...