Enhanced self-administration of the CB1 receptor agonist WIN55,212-2 in olfactory bulbectomized rats: evaluation of possible serotonergic and dopaminergic underlying mechanisms

• Main Authors: Petra eAmchova (Author), Jana eKucerova (Author), Valentina eGiugliano (Author), Zuzana eBabinska (Author), Mary Tresa Zanda (Author), Maria eScherma (Author), Ladislav eDusek (Author), Paola eFadda (Author), Vincenzo eMicale (Author), Alexandra eSulcova (Author), Walter eFratta (Author), Liana eFattore (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Depression has been associated with drug consumption, including heavy or problematic cannabis use. According to an animal model of depression and substance use disorder comorbidity, we combined the olfactory bulbectomy model of depression with intravenous drug self-administration procedure to verify...