Deterioration of muscle force and contractile characteristics are early pathological events in spinal and bulbar muscular atrophy mice

• Main Authors: Anna L. Gray (Author), Leonette Annan (Author), James R. T. Dick (Author), Albert R. La Spada (Author), Michael G. Hanna (Author), Linda Greensmith (Author), Bilal Malik (Author)
• Format: Book
• Published: The Company of Biologists, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Spinal and bulbar muscular atrophy (SBMA), also known as Kennedy's Disease, is a late-onset X-linked progressive neuromuscular disease, which predominantly affects males. The pathological hallmarks of the disease are selective loss of spinal and bulbar motor neurons, accompanied by weakness, at...