Protective Effect of Curcumin against Sodium Salicylate-Induced Oxidative Kidney Damage, Nuclear Factor-Kappa Dysregulation, and Apoptotic Consequences in Rats

• Main Authors: Yasmina M. Abd-Elhakim (Author), Attia A. A. Moselhy (Author), Adil Aldhahrani (Author), Rasha R. Beheiry (Author), Wafaa A. M. Mohamed (Author), Mohamed Mohamed Soliman (Author), Bayan A. Saffaf (Author), Maha M. El Deib (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study examined the effect of sodium salicylates (SS), alone and in combination with curcumin (CUR), on kidney function and architecture in rats. Five rat groups were given 1 mL physiological saline/rat orally, 1 mL olive oil/rat orally, 50 mg CUR/kg bwt orally, 300 mg SS/kg bwt intraperitoneall...