Ruthenium complex with benznidazole and nitric oxide as a new candidate for the treatment of chagas disease.

• Main Authors: Renata Sesti-Costa (Author), Zumira A Carneiro (Author), Maria C Silva (Author), Maíta Santos (Author), Grace K Silva (Author), Cristiane Milanezi (Author), Roberto S da Silva (Author), João S Silva (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chagas disease remains a serious medical and social problem in Latin America and is an emerging concern in nonendemic countries as a result of population movement, transfusion of infected blood or organs and congenital transmission. The current treatment of infected patients is unsatisfactory due to...