Discovery of novel FGFR4 inhibitors through a build-up fragment strategy
AbstractHepatocellular carcinoma (HCC) is a leading cause of cancer-related death. FGFR4 has been implicated in HCC progression, making it a promising therapeutic target. We introduce an approach for identifying novel FGFR4 inhibitors by sequentially adding fragments to a common warhead unit. This s...
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Main Authors: | , , , , , |
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Format: | Book |
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Taylor & Francis Group,
2024-12-01T00:00:00Z.
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Internet
Connect to this object online.3rd Floor Main Library
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A1234.567 |
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Copy 1 | Available |