Discovery of novel FGFR4 inhibitors through a build-up fragment strategy

AbstractHepatocellular carcinoma (HCC) is a leading cause of cancer-related death. FGFR4 has been implicated in HCC progression, making it a promising therapeutic target. We introduce an approach for identifying novel FGFR4 inhibitors by sequentially adding fragments to a common warhead unit. This s...

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Bibliographic Details
Main Authors: Jihyung Kim (Author), Chang Gyun Im (Author), Kyujin Oh (Author), Ji Min Lee (Author), Fatimah Al-Rubaye (Author), Kyung Hoon Min (Author)
Format: Book
Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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