Implementation of an NGS panel for clinical practice in paraffin-embedded tissue samples from locally advanced and metastatic melanoma patients

• Main Authors: Paola Castillo (Author), Marta Marginet (Author), Pedro Jares (Author), Mireia García (Author), Elena Gonzalvo (Author), Ana Arance (Author), Adriana García (Author), Llucia Alos (Author), Cristina Teixido (Author)
• Format: Book
• Published: Open Exploration Publishing Inc., 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: Single biomarker diagnostic test of BRAFV600 locus in metastatic melanoma is mandatory for treatment decision; however, multiple-gene based techniques, such as targeted next-generation sequencing (NGS) are being used to maximize the number of patients that can benefit from a targeted therapy. T...