Epigenetic regulatory mechanism of ADAMTS12 expression in osteoarthritis

• Main Authors: Shu Yang (Author), Xuanping Zhou (Author), Zhen Jia (Author), Mali Zhang (Author), Minghao Yuan (Author), Yizhao Zhou (Author), Jing Wang (Author), Duo Xia (Author)
• Format: Book
• Published: BMC, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Osteoarthritis (OA) is a degenerative joint disease with lacking effective prevention targets. A disintegrin and metalloproteinase with thrombospondin motifs 12 (ADAMTS12) is a member of the ADAMTS family and is upregulated in OA pathologic tissues with no fully understood molecu...