A novel mechanism of streptomycin resistance in Yersinia pestis: Mutation in the rpsL gene.

• Main Authors: Ruixia Dai (Author), Jian He (Author), Xi Zha (Author), Yiting Wang (Author), Xuefei Zhang (Author), He Gao (Author), Xiaoyan Yang (Author), Juan Li (Author), Youquan Xin (Author), Yumeng Wang (Author), Sheng Li (Author), Juan Jin (Author), Qi Zhang (Author), Jixiang Bai (Author), Yao Peng (Author), Hailian Wu (Author), Qingwen Zhang (Author), Baiqing Wei (Author), Jianguo Xu (Author), Wei Li (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Streptomycin is considered to be one of the effective antibiotics for the treatment of plague. In order to investigate the streptomycin resistance of Y. pestis in China, we evaluated streptomycin susceptibility of 536 Y. pestis strains in China in vitro using the minimal inhibitory concentration (MI...