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The total polyphenolic glycoside extract of Lamiophlomis rotata ameliorates hepatic fibrosis through apoptosis by TGF-β/Smad signaling pathway

Highlights Chemical composition of TPRL was identified by UPLC-Q/TOF/MSn in the profile of total ion current. TPRL was initially demostrated the effects of anti-hepatic fibrosis in vitro and in vivo. TPRL ameliorates hepatic fibrosis through apoptosis by TGF-β/Smad signaling pathway.

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Bibliographic Details
Main Authors: Guoguo Wan (Author), Zhiwei Chen (Author), Lei Lei (Author), Xiaoyu Geng (Author), Yi Zhang (Author), Congwen Yang (Author), Wenfu Cao (Author), Zheng Pan (Author)
Format: Book
Published: BMC, 2023-02-01T00:00:00Z.
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Summary:Highlights Chemical composition of TPRL was identified by UPLC-Q/TOF/MSn in the profile of total ion current. TPRL was initially demostrated the effects of anti-hepatic fibrosis in vitro and in vivo. TPRL ameliorates hepatic fibrosis through apoptosis by TGF-β/Smad signaling pathway.
Item Description:10.1186/s13020-023-00723-x
1749-8546

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