Development and validation of an LC-MS/MS method for pharmacokinetic study of lobetyolin in rats

• Váldodahkkit: Haitao Tian (Dahkki), Pan Zhao (Dahkki), Jing Li (Dahkki), Zhipeng Deng (Dahkki), Gaobin Pu (Dahkki), Hong Wang (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Universidade de São Paulo, 2023-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Abstract A simple and selective liquid chromatography tandem with mass spectrometry (LC-MS/ MS) method for quantification of lobetyolin in rat plasma was developed and validated. Chromatographic separation was achieved on a Thermo ODS C18 reversed-phase column using 0.1% aqueous formic acid-methanol...