Probing the role of an invariant active site His in family GH1 β-glycosidases

• Main Authors: Andrea Strazzulli (Author), Giuseppe Perugino (Author), Marialuisa Mazzone (Author), Mosè Rossi (Author), Stephen G. Withers (Author), Marco Moracci (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The reaction mechanism of glycoside hydrolases belonging to family 1 (GH1) of carbohydrate-active enzymes classification, hydrolysing β-O-glycosidic bonds, is well characterised. This family includes several thousands of enzymes with more than 20 different EC numbers depending on the sugar glycone r...