Curcumin relieves corticosterone‐induced behaviour deficits via PGC‐1α‐mediated mitochondrial biogenesis and mitophagy

• Hauptverfasser: Wen‐yuan Zhang (Verfasst von), Ya‐jing Wu (Verfasst von), Yu‐jin Guo (Verfasst von), Chang‐shui Wang (Verfasst von), Xiu‐zhen Long (Verfasst von), Pei Jiang (Verfasst von)
• Format: Buch
• Veröffentlicht: Wiley, 2022-12-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Curcumin (CUR), an FDA‐approved natural product, has been found to be clinically effective in treating depression. However, the underlying mechanism remains elusive. PGC‐1α is a key factor in regulating mitochondrial health and depression. This study randomly divided C57BL/6 mice or culture...