A multifunctional cross-validation high-throughput screening protocol enabling the discovery of new SHP2 inhibitors
The protein tyrosine phosphatase Src homology phosphotyrosyl phosphatase 2 (SHP2) is implicated in various cancers, and targeting SHP2 has become a promising therapeutic approach. We herein described a robust cross-validation high-throughput screening protocol that combined the fluorescence-based en...
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| Main Authors: | , , , , |
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| Formato: | Livro |
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Elsevier,
2021-03-01T00:00:00Z.
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