A multifunctional cross-validation high-throughput screening protocol enabling the discovery of new SHP2 inhibitors

The protein tyrosine phosphatase Src homology phosphotyrosyl phosphatase 2 (SHP2) is implicated in various cancers, and targeting SHP2 has become a promising therapeutic approach. We herein described a robust cross-validation high-throughput screening protocol that combined the fluorescence-based en...

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Asıl Yazarlar: Yihui Song (Yazar), Min Zhao (Yazar), Yahong Wu (Yazar), Bin Yu (Yazar), Hong-Min Liu (Yazar)
Materyal Türü: Kitap
Baskı/Yayın Bilgisi: Elsevier, 2021-03-01T00:00:00Z.
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